Measure the ID of both holes, add them and divide by two.... Measure the distance between the INSIDE (closest) edges of the two holes, and add the sum of the half diameters.... This works for any size holes, even ones that are different diameters, and can be done easily with digital calipers....Bob
I have done the best with putting something in the hole, a screw or set screw if it is threaded, a twist drill shank if it is a smooth hole (I have gauge pins in .001 incrememts from .01 to .900 but not many folks do) then measure over the objects and subtract the radius of each if they are different, or the dia if they are both the same size hole.Bill
Measuring from front edge of hole to front edge of second hole is the best way. However, to improve on that thought to find the exact measurement, is to simply put the screws into the holes and use the edge of the screws to measure from. That way the calipers have something they can press against to take the measurement.
Using the inside jaws of your caliper measure the inside distance between your two holesUse the outside jaws to measure the outside distance between the two holes.Add the two together and divide by 2