I had a similar issue and it turned out to be loose electrical/ mechanical connections at the hot end.
Is your printer in an enclosure? Give that a try as well, when you're able.
When you lost extrusion and heard the extruder click was the hot end still up to temperature? You could have lost the hot end temp causing the lost extrusion. This is exactly the same problem I had. Ran great on short prints but would have extruder issues on long prints. I found the hot end mounting screws loose along with the thermistor wire.As for your drier box you just need to bake it longer 12 to 14 hrs should do.