Size 'em if you need to!.... They are designed so that the back of the nose is groove diameter, and the drive band 0.002" larger, because most chambers are about that much oversize.... However, not all barrels are the same, so if your chamber is long enough and they won't chamber properly, then sizing them until they do is perfectly acceptable.... I find maximum velocity at about 0.001" under groove diameter, but maximum accuracy may be there or up to 0.001" over groove, again it depends on your barrel.... If you do size them, I would do them nose first so that they guide themselves into the sizing bushing, not sure they would stay straight if you do them base first (but I have never tried it)....Bob