I found that owning multiple calibers has increased my range accuracy. Little to no wind, .177 is fine. Add a little crosswind and I go to either the .22 or the .25. It's amazing how much more accurate you can be when you use the heavier weights to your advantage. Not that a .177 doesn't perform well with the know how in the wind, it's just a bit more affected. The distance of the target also plays a role. Probably the most accurate platform I owned was a .22 marauder with a hammer forged barrel shooting the 18.13 JSBs. All in all it really only matters what YOU deem you need.